FASD is an umbrella term covering a range of birth defects and brain damage resulting from prenatal exposure to alcohol. The term FASD is not used as a clinical diagnosis, but encompasses diagnoses such as Fetal Alcohol Syndrome (FAS) and related disorders. FAS is diagnosed when a child shows retarded growth, a specific pattern of minor facial anomalies and neurological damage.
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Children who do not show all the features of FAS may receive a diagnosis of partial FAS, Fetal Alcohol Effects, Alcohol-Related Neurodevelopmental Disorder, or Alcohol-Related Birth Defects. All persons with FASD have lifelong cognitive, social and behavioral disabilities.
Alcohol reduces fertility, increases the risk of miscarriage and causes brain damage and birth defects . Prenatal exposure to alcohol can cause cognitive damage, learning disorders and mental retardation, as well as behavioral disorders such as ADHD and autism. Poor motor coordination is common. Difficulty with judgment and under-standing social situations contributes to long term outcomes such as unemployment, psychiatric illness, and criminality . Even moderate drinking or a single binge can cause permanent damage [3 4 5]. The severity of FASD depends on factors such as the level of exposure, the developmental stage of the fetus . and nutritional status of the mother .
The prevalence of FASD has not been studied in all areas of the world. Diagnosis requires special medical expertise, so many cases are missed or misdiagnosed . In the US, the prevalence of FASD is estimated at 1% , in Italy at 2 to 4% , and even higher in South Africa  and Russia .
Children with FASD are more likely to grow up in foster care, and youth with FASD are 19 times more likely to be incarcerated than youth without FASD . In a population exposed to alcohol in utero, educational achievement was lower, while broken relationships and unemployment were higher . Prenatal exposure to alcohol has thus been termed a “poverty trap” .
There is no cure for FASD, but it can be prevented. The incidence of FASD can be reduced by public information campaigns, support of pregnant women, and clear preconception advice .
1. Health Council of the Netherlands. Risks of alcohol consumption related to conception, pregnancy and breastfeeding. The Hague: Health Council of the Netherlands, 2005; publication no. 2004/22. ISBN 90-5549-000-8 [Summary in EN] [Full text in NL]
4. Barr, HM et al. Binge drinking during pregnancy as a predictor of psychiatric disorders on the Structured Clinical Interview for DSM-IV in young adult offspring. Am. J. Psychiatry 163, 1061-1065 (2006). [Full text]
5. Nilsson, JP. Does a pint a day affect your child's pay? The effect of prenatal alcohol exposure on adult outcomes. Working paper 2008:4. 2008. Uppsala, IFAU--Institute for Labor Market Policy Evaluation. [Full text]
7. Keen, CL et al. The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example. Biofactors 36(2):125-35 (2010). [Full text]
8. Vagnarelli, F et al. A survey of Italian and Spanish neonatologists and paediatricians regarding awareness of the diagnosis of FAS and FASD and maternal ethanol use during pregnancy. BMC Pediatr. 2011 Jun 6;11:51. doi: 10.1186/1471-2431-11-51 [Full text]